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The Surface of Protein λ(6-85) Can Act as a Template for Recurring PEG Structure

PEGylated proteins play an increasingly important role in pharmaceutical drug delivery. We recently showed that short PEG chains can affect protein structure, even when they are not making extensive contact with the protein surface. In contrast, PEG is generally assumed to form a relatively unstruct...

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Vydáno v:Biochemistry
Hlavní autoři: Chao, Shu-Han, Schäfer, Jan, Gruebele, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044911/
https://ncbi.nlm.nih.gov/pubmed/28714684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00215
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