Generation of Novel Anti-MUC1 Monoclonal Antibodies with Designed Carbohydrate Specificities Using MUC1 Glycopeptide Library

[Image: see text] Numerous anti-mucin 1 (anti-MUC1) antibodies that recognize O-glycan core structures have already been developed. However, most of them show low specificities toward O-glycan structures and/or low affinity toward a monovalent epitope. In this study, using an MUC1 glycopeptide libra...

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Udgivet i:ACS Omega
Main Authors: Naito, Shoichi, Takahashi, Tatsuya, Onoda, Junji, Uemura, Shoko, Ohyabu, Naoki, Takemoto, Hiroshi, Yamane, Shoji, Fujii, Ikuo, Nishimura, Shin-Ichiro, Numata, Yoshito
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044872/
https://ncbi.nlm.nih.gov/pubmed/30023556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00708
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