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Synthesis and Immunological Evaluation of a MUC1 Glycopeptide Incorporated into l-Rhamnose Displaying Liposomes

MUC1 variable number tandem repeats (VNTRs) conjugated to tumor-associated carbohydrate antigens (TACAs) have been shown to break self-tolerance in humanized MUC1 transgenic mice. Therefore, we hypothesize that a MUC1 VNTR TACA-conjugate can be successfully formulated into a liposome-based anti-canc...

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Main Authors: Sarkar, Sourav, Salyer, Alex C. D., Wall, Katherine A., Sucheck, Steven J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623543/
https://ncbi.nlm.nih.gov/pubmed/23444835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300422a
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