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Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism

[Image: see text] Aldehyde oxidase (AO) is a molybdenum-containing enzyme involved in the clearance of drug compounds containing aldehydes and N-containing heterocyclic fragments. AO has gained considerable interest in recent years because of examples of too fast clearance of drug compounds in devel...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Montefiori, Marco, Jørgensen, Flemming Steen, Olsen, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044498/
https://ncbi.nlm.nih.gov/pubmed/30023718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00658
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