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Detecting germline BAP1 mutations in patients with peritoneal mesothelioma: benefits to patient and family members

Germline mutations in the BRCA-1 associated tumor protein 1 (BAP1) increase susceptibility to mesothelioma and other cancers. We describe a patient with a family history of peritoneal mesothelioma, who developed malignant peritoneal mesothelioma at age 45 in the absence of known asbestos exposure. T...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Kittaneh, Muaiad, Berkelhammer, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044070/
https://ncbi.nlm.nih.gov/pubmed/30001711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1559-7
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