Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors

Most general anesthetics enhance GABA type A (GABA(A)) receptor activity at clinically relevant concentrations. Sites of action of volatile anesthetics on the GABA(A) receptor remain unknown, whereas sites of action of many intravenous anesthetics have been identified in GABA(A) receptors by using p...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Woll, Kellie A., Zhou, Xiaojuan, Bhanu, Natarajan V., Garcia, Benjamin A., Covarrubias, Manuel, Miller, Keith W., Eckenhoff, Roderic G.
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044061/
https://ncbi.nlm.nih.gov/pubmed/29505303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701347R
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