Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors

Most general anesthetics enhance GABA type A (GABA(A)) receptor activity at clinically relevant concentrations. Sites of action of volatile anesthetics on the GABA(A) receptor remain unknown, whereas sites of action of many intravenous anesthetics have been identified in GABA(A) receptors by using p...

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Veröffentlicht in:FASEB J
Hauptverfasser: Woll, Kellie A., Zhou, Xiaojuan, Bhanu, Natarajan V., Garcia, Benjamin A., Covarrubias, Manuel, Miller, Keith W., Eckenhoff, Roderic G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044061/
https://ncbi.nlm.nih.gov/pubmed/29505303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701347R
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