Inflammation, von Willebrand factor, and ADAMTS13

Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF, assembly of hyperadhesive VWF strings and fibers, cleavage by ADAMTS13, and adhesion and deposition of VWF-platelet thrombi...

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Bibliographic Details
Published in:Blood
Main Authors: Chen, Junmei, Chung, Dominic W.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2018
Subjects:
Review Series
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043979/
https://ncbi.nlm.nih.gov/pubmed/29866815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-769000
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