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ADAMTS‐13 and von Willebrand factor: a dynamic duo

von Willebrand factor (VWF) is a key player in hemostasis, acting as a carrier for factor VIII and capturing platelets at sites of vascular damage. To capture platelets, it must undergo conformational changes, both within its A1 domain and at the macromolecular level through A2 domain unfolding. Its...

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Detalles Bibliográficos
Publicado en:J Thromb Haemost
Main Authors: South, K., Lane, D. A.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814862/
https://ncbi.nlm.nih.gov/pubmed/29108103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13898
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