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Phospholipase Cγ2 is critical for Ca(2+) flux and cytokine production in anti-fungal innate immunity of human corneal epithelial cells

BACKGROUND: Fungal keratitis (FK) is a sight-threatening disease, accounting for a significant portion with its complex presentation, suboptimal efficacy of the existing therapies and uncontrollable excessive innate inflammation. Phospholipase C-γ2 (PLCγ2) is a non-receptor tyrosine kinase that play...

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Detalhes bibliográficos
Publicado no:BMC Ophthalmol
Main Authors: Peng, Xudong, Zhao, Guiqiu, Lin, Jing, Qu, Jianqiu, Zhang, Yingxue, Li, Cui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043966/
https://ncbi.nlm.nih.gov/pubmed/30005593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-018-0847-6
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