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Phospholipase Cγ2 is critical for Ca(2+) flux and cytokine production in anti-fungal innate immunity of human corneal epithelial cells
BACKGROUND: Fungal keratitis (FK) is a sight-threatening disease, accounting for a significant portion with its complex presentation, suboptimal efficacy of the existing therapies and uncontrollable excessive innate inflammation. Phospholipase C-γ2 (PLCγ2) is a non-receptor tyrosine kinase that play...
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| Publicat a: | BMC Ophthalmol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6043966/ https://ncbi.nlm.nih.gov/pubmed/30005593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-018-0847-6 |
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