Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin

Epithelial cell adhesion molecule (EpCAM)-targeted capture remains the most common isolation strategy for circulating tumor cells (CTCs). However, epithelial-to-mesenchymal transition (EMT) leads to decreased epithelial EpCAM expression affecting the optimal CTC capture. In this study, we tested a c...

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Vydáno v:J Circ Biomark
Hlavní autoři: Po, Joseph W, Roohullah, Aflah, Lynch, David, DeFazio, Anna, Harrison, Michelle, Harnett, Paul R, Kennedy, Catherine, de Souza, Paul, Becker, Therese M
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043919/
https://ncbi.nlm.nih.gov/pubmed/30013673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1849454418782617
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