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Long Feeding High-Fat Diet Induces Hypothalamic Oxidative Stress and Inflammation, and Prolonged Hypothalamic AMPK Activation in Rat Animal Model

Scope: The hypothalamus is a key brain region involved in the control of feeding and energy expenditure. Hypothalamic inflammation and oxidative stress are landmarks of both obesity and aging processes, although the molecular mechanisms are still unknown. Therefore, with the aim to understand the ne...

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Publicat a:Front Physiol
Autors principals: Cavaliere, Gina, Viggiano, Emanuela, Trinchese, Giovanna, De Filippo, Chiara, Messina, Antonietta, Monda, Vincenzo, Valenzano, Anna, Cincione, Raffaele I., Zammit, Christian, Cimmino, Fabiano, Catapano, Angela, Sessa, Francesco, Messina, Giovanni, Monda, Marcellino, Crispino, Marianna, Mollica, Maria Pina
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043859/
https://ncbi.nlm.nih.gov/pubmed/30034345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00818
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