Long Feeding High-Fat Diet Induces Hypothalamic Oxidative Stress and Inflammation, and Prolonged Hypothalamic AMPK Activation in Rat Animal Model

Scope: The hypothalamus is a key brain region involved in the control of feeding and energy expenditure. Hypothalamic inflammation and oxidative stress are landmarks of both obesity and aging processes, although the molecular mechanisms are still unknown. Therefore, with the aim to understand the ne...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Cavaliere, Gina, Viggiano, Emanuela, Trinchese, Giovanna, De Filippo, Chiara, Messina, Antonietta, Monda, Vincenzo, Valenzano, Anna, Cincione, Raffaele I., Zammit, Christian, Cimmino, Fabiano, Catapano, Angela, Sessa, Francesco, Messina, Giovanni, Monda, Marcellino, Crispino, Marianna, Mollica, Maria Pina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043859/
https://ncbi.nlm.nih.gov/pubmed/30034345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00818
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