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Angiotensin II-induced end organ damage in mice is attenuated by human exosomes and by an exosomal Y RNA fragment

Hypertension often leads to cardiovascular disease (CVD) and kidney dysfunction. Exosomes secreted from cardiosphere-derived cells (CDC-exo) and their most abundant small RNA constituent, the Y RNA fragment EV-YF1, exert therapeutic benefits after myocardial infarction. Here, we investigated the eff...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Cambier, Linda, Giani, Jorge F., Liu, Weixin, Ijichi, Takeshi, Echavez, Antonio K., Valle, Jackelyn, Marbán, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043385/
https://ncbi.nlm.nih.gov/pubmed/29866742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11239
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