Exosomes from cardiac stem cells amplify their own bioactivity by converting fibroblasts to therapeutic cells

BACKGROUND: Cardiosphere-derived cells (CDCs) mediate therapeutic regeneration in patients after myocardial infarction and are undergoing further clinical testing for cardiomyopathy. The beneficial effects of CDCs are mediated by the secretion of exosomes and possibly other extracellular membrane ve...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Tseliou, Eleni, Fouad, Joseph, Reich, Heidi, Slipczuk, Leandro, de Couto, Geoffrey, Aminzadeh, Mark, Middleton, Ryan, Valle, Jackelyn, Weixin, Liu, Marbán, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593504/
https://ncbi.nlm.nih.gov/pubmed/26248985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2015.05.068
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