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Exosomes from cardiac stem cells amplify their own bioactivity by converting fibroblasts to therapeutic cells

BACKGROUND: Cardiosphere-derived cells (CDCs) mediate therapeutic regeneration in patients after myocardial infarction and are undergoing further clinical testing for cardiomyopathy. The beneficial effects of CDCs are mediated by the secretion of exosomes and possibly other extracellular membrane ve...

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Publicat a:J Am Coll Cardiol
Autors principals: Tseliou, Eleni, Fouad, Joseph, Reich, Heidi, Slipczuk, Leandro, de Couto, Geoffrey, Aminzadeh, Mark, Middleton, Ryan, Valle, Jackelyn, Weixin, Liu, Marbán, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593504/
https://ncbi.nlm.nih.gov/pubmed/26248985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2015.05.068
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