Bradykinin stimulates renal Na(+) and K(+) excretion by inhibiting the K(+) channel (Kir4.1) in the distal convoluted tubule

Stimulation of bradykinin (BK) B2 receptor (BK2R) has been shown to increase renal Na(+) excretion. The aim of the present study is to explore the role of BK2R in regulating Kir4.1 and Na-Cl cotransporter (NCC) in the distal convoluted tubule (DCT). Immunohistochemical studies demonstrated that BK2R...

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Bibliografiske detaljer
Udgivet i:Hypertension
Main Authors: Zhang, Dan-Dan, Gao, Zhong-Xiuzi, Vio, Carlos P, Xiao, Yu, Wu, Peng, Zhang, Hao, Guo, Xi-Wen, Meng, Xin-Xin, Gu, Li, Wang, Jun-Lin, Duan, Xin-Peng, Lin, Dao-Hong, Wang, Wen-Hui, Gu, Ruimin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043363/
https://ncbi.nlm.nih.gov/pubmed/29915013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11070
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