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Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity

Mitochondria are integral to cellular energy metabolism and ATP production, and are involved in regulating many cellular processes. Mitochondria produce reactive oxygen species (ROS) that can damage cellular components but that also participate in signal transduction. The kinase ATM, which is mutate...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Zhang, Yichong, Lee, Ji-Hoon, Paull, Tanya T., Gehrke, Sarah, D’alessandro, Angelo, Dou, Qianhui, Gladyshev, Vadim N., Schroeder, Elizabeth A., Steyl, Samantha K., Christian, Brooke E., Shadel, Gerald S.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042875/
https://ncbi.nlm.nih.gov/pubmed/29991649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq0702
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