Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress

The denitrosylase S‐nitrosoglutathione reductase (GSNOR) has been suggested to sustain mitochondrial removal by autophagy (mitophagy), functionally linking S‐nitrosylation to cell senescence and aging. In this study, we provide evidence that GSNOR is induced at the translational level in response to...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Cirotti, Claudia, Rizza, Salvatore, Giglio, Paola, Poerio, Noemi, Allega, Maria Francesca, Claps, Giuseppina, Pecorari, Chiara, Lee, Ji‐Hoon, Benassi, Barbara, Barilà, Daniela, Robert, Caroline, Stamler, Jonathan S, Cecconi, Francesco, Fraziano, Maurizio, Paull, Tanya T, Filomeni, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788447/
https://ncbi.nlm.nih.gov/pubmed/33245190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050500
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