Mitochondrial Ca(2+) flux modulates spontaneous electrical activity in ventricular cardiomyocytes

INTRODUCTION: Ca(2+) release from sarcoplasmic reticulum (SR) is known to contribute to automaticity via the cytoplasmic Na(+)-Ca(2+) exchanger (NCX). Mitochondria participate in Ca(2+) cycling. We studied the role of mitochondrial Ca(2+) flux in ventricular spontaneous electrical activity. METHODS:...

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Publicat a:PLoS One
Autors principals: Xie, An, Zhou, Anyu, Liu, Hong, Shi, Guangbin, Liu, Man, Boheler, Kenneth R., Dudley, Samuel C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042741/
https://ncbi.nlm.nih.gov/pubmed/30001390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200448
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