Mitochondrial Ca(2+) Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy

BACKGROUND: Heart failure (HF) is associated with increased arrhythmia risk and triggered activity. Abnormal Ca(2+) handling is thought to underlie triggered activity, and mitochondria participate in Ca(2+) homeostasis. METHODS AND RESULTS: A model of nonischemic HF was induced in C57BL/6 mice by hy...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Xie, An, Song, Zhen, Liu, Hong, Zhou, Anyu, Shi, Guangbin, Wang, Qiongying, Gu, Lianzhi, Liu, Man, Xie, Lai‐Hua, Qu, Zhilin, Dudley, Samuel C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015427/
https://ncbi.nlm.nih.gov/pubmed/29627768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007805
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