Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth

Precision cancer therapy requires on the one hand detailed knowledge about a tumor’s driver oncogenes and on the other hand an effective targeted therapy that specifically inhibits these oncogenes. While the determination of genomic landscape of a tumor has reached a very precise level, the respecti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bäumer, Nicole, Rehkämper, Jan, Appel, Neele, Terheyden, Lisa, Hartmann, Wolfgang, Wardelmann, Eva, Buchholz, Frank, Müller-Tidow, Carsten, Berdel, Wolfgang E., Bäumer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042707/
https://ncbi.nlm.nih.gov/pubmed/30001368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200163
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