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Maintenance of Leukemia-Initiating Cells Is Regulated by the CDK Inhibitor Inca1
Functional differences between healthy progenitor and cancer initiating cells may provide unique opportunities for targeted therapy approaches. Hematopoietic stem cells are tightly controlled by a network of CDK inhibitors that govern proliferation and prevent stem cell exhaustion. Loss of Inca1 led...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272264/ https://ncbi.nlm.nih.gov/pubmed/25525809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115578 |
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