Maintenance of Leukemia-Initiating Cells Is Regulated by the CDK Inhibitor Inca1

Functional differences between healthy progenitor and cancer initiating cells may provide unique opportunities for targeted therapy approaches. Hematopoietic stem cells are tightly controlled by a network of CDK inhibitors that govern proliferation and prevent stem cell exhaustion. Loss of Inca1 led...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bäumer, Nicole, Bäumer, Sebastian, Berkenfeld, Frank, Stehling, Martin, Köhler, Gabriele, Berdel, Wolfgang E., Müller-Tidow, Carsten, Tschanter, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272264/
https://ncbi.nlm.nih.gov/pubmed/25525809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115578
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