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Proteinase-Activated Receptor 1 (PAR1) Regulates Leukemic Stem Cell Functions

External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknow...

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Detalhes bibliográficos
Main Authors: Bäumer, Nicole, Krause, Annika, Köhler, Gabriele, Lettermann, Stephanie, Evers, Georg, Hascher, Antje, Bäumer, Sebastian, Berdel, Wolfgang E., Müller-Tidow, Carsten, Tickenbrock, Lara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989293/
https://ncbi.nlm.nih.gov/pubmed/24740120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094993
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