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A Magnetic Bead-Integrated Chip for the Large Scale Manufacture of Normalized esiRNAs
The chemically-synthesized siRNA duplex has become a powerful and widely used tool for RNAi loss-of-function studies, but suffers from a high off-target effect problem. Recently, endoribonulease-prepared siRNA (esiRNA) has been shown to be an attractive alternative due to its lower off-target effect...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384639/ https://ncbi.nlm.nih.gov/pubmed/22761791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039419 |
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