Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser(422) containing epitope on pathological tau

Aggregation of tau protein and spreading of tau aggregates are pivotal pathological processes in a range of neurological disorders. Accumulating evidence suggests that immunotherapy targeting tau may be a viable therapeutic strategy. We have previously described the isolation of antibody CBTAU-22.1...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Acta Neuropathol Commun
Päätekijät: van Ameijde, Jeroen, Crespo, Rosa, Janson, Roosmarijn, Juraszek, Jarek, Siregar, Berdien, Verveen, Hanneke, Sprengers, Imke, Nahar, Tariq, Hoozemans, Jeroen J., Steinbacher, Stefan, Willems, Roland, Delbroek, Lore, Borgers, Marianne, Dockx, Koen, Van Kolen, Kristof, Mercken, Marc, Pascual, Gabriel, Koudstaal, Wouter, Apetri, Adrian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042391/
https://ncbi.nlm.nih.gov/pubmed/30001207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0562-9
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