Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis

Obesity and related metabolic diseases are becoming worldwide epidemics that lead to increased death rates and heavy health care costs. Effective treatment options have not been found yet. Here, based on the observation that baicalin, a flavonoid from the herbal medicine Scutellaria baicalensis, has...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dai, Jianye, Liang, Kai, Zhao, Shan, Jia, Wentong, Liu, Yuan, Wu, Hongkun, Lv, Jia, Cao, Chen, Chen, Tao, Zhuang, Shentian, Hou, Xiaomeng, Zhou, Shijie, Zhang, Xiannian, Chen, Xiao-Wei, Huang, Yanyi, Xiao, Rui-Ping, Wang, Yan-Ling, Luo, Tuoping, Xiao, Junyu, Wang, Chu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042128/
https://ncbi.nlm.nih.gov/pubmed/29891721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801745115
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