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Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity

CD11c, also known as integrin alpha X, is the most widely used defining marker for dendritic cells (DCs). CD11c can bind complement iC3b and mediate phagocytosis in vitro, for which it is also referred to as complement receptor 4. However, the functions of this prominent marker protein in DCs, espec...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wu, Jiaxi, Wu, Huaizhu, An, Jinping, Ballantyne, Christie M., Cyster, Jason G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042080/
https://ncbi.nlm.nih.gov/pubmed/29891680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805542115
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