Essential Role of CD11a in CD8(+) T-Cell Accumulation and Activation in Adipose Tissue

OBJECTIVE: T cells, particularly CD8(+) T cells, are major participants in obesity-linked adipose tissue (AT) inflammation. We examined the mechanisms of CD8(+) T-cell accumulation and activation in AT and the role of CD11a, a β2 integrin. APPROACH AND RESULTS: CD8(+) T cells in AT of obese mice sho...

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Autors principals: Jiang, Erlie, Perrard, Xiaoyuan Dai, Yang, Donglin, Khan, Ilvira M., Perrard, Jerry L., Smith, C. Wayne, Ballantyne, Christie M., Wu, Huaizhu
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060534/
https://ncbi.nlm.nih.gov/pubmed/24158516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302077
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