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EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture
Splenic dendritic cells (DCs) present blood-borne antigens to lymphocytes to promote T cell and antibody responses. The cues involved in positioning DCs in areas of antigen exposure in the spleen are undefined. Here we show that CD4(+) DCs highly express EBI2 and migrate to its oxysterol ligand, 7α,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654440/ https://ncbi.nlm.nih.gov/pubmed/23682316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00757 |
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