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EBI2 augments Tfh cell fate by promoting interaction with IL2-quenching dendritic cells

T follicular helper (Tfh) cells are a CD4 T cell subset that is important for supporting plasma cell and germinal center (GC) responses(1,2). The initial induction of Tfh cell properties occurs within the first few days following activation by antigen recognition on dendritic cells (DCs), though how...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Li, Jianhua, Lu, Erick, Yi, Tangsheng, Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883664/
https://ncbi.nlm.nih.gov/pubmed/27147029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17947
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