CAME: identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

MOTIVATION: Chromatin accessibility plays a key role in epigenetic regulation of gene activation and silencing. Open chromatin regions allow regulatory elements such as transcription factors and polymerases to bind for gene expression while closed chromatin regions prevent the activity of transcript...

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Publicat a:Bioinformatics
Autors principals: Piao, Yongjun, Lee, Seong Keon, Lee, Eun-Joon, Robertson, Keith D, Shi, Huidong, Ryu, Keun Ho, Choi, Jeong-Hyeon
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041946/
https://ncbi.nlm.nih.gov/pubmed/28035030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw785
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