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CAME: identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

MOTIVATION: Chromatin accessibility plays a key role in epigenetic regulation of gene activation and silencing. Open chromatin regions allow regulatory elements such as transcription factors and polymerases to bind for gene expression while closed chromatin regions prevent the activity of transcript...

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Podrobná bibliografie
Vydáno v:Bioinformatics
Hlavní autoři: Piao, Yongjun, Lee, Seong Keon, Lee, Eun-Joon, Robertson, Keith D, Shi, Huidong, Ryu, Keun Ho, Choi, Jeong-Hyeon
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041946/
https://ncbi.nlm.nih.gov/pubmed/28035030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw785
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