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AltHapAlignR: improved accuracy of RNA-seq analyses through the use of alternative haplotypes
MOTIVATION: Reliance on mapping to a single reference haplotype currently limits accurate estimation of allele or haplotype-specific expression using RNA-sequencing, notably in highly polymorphic regions such as the major histocompatibility complex. RESULTS: We present AltHapAlignR, a method incorpo...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6041798/ https://ncbi.nlm.nih.gov/pubmed/29514179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty125 |
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