Effects of an ActRIIB.Fc Ligand Trap on Cardiac Function in Simian Immunodeficiency Virus-Infected Male Rhesus Macaques

An important safety consideration in the use of antagonists of myostatin and activins is whether these drugs induce myocardial hypertrophy and impair cardiac function. The current study evaluated the effects of a soluble ActRIIB receptor Fc fusion protein (ActRIIB.Fc), a ligand trap for TGF-β/activi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Endocr Soc
Päätekijät: Guo, Wen, Pencina, Karol M, Gagliano-Jucá, Thiago, Jasuja, Ravi, Morris, Nancy, O’Connell, Karyn E, Westmoreland, Susan, Bhasin, Shalender
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Endocrine Society 2018
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041778/
https://ncbi.nlm.nih.gov/pubmed/30019021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2018-00099
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