Administration of an activin receptor IIB ligand trap protects male juvenile rhesus macaques from simian immunodeficiency virus-associated bone loss

HIV-infected individuals are at an increased risk of osteoporosis despite effective viral suppression. Observations that myostatin null mice have increased bone mass led us to hypothesize that simian immunodeficiency virus (SIV)-associated bone loss may be attenuated by blocking myostatin/TGFβ signa...

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發表在:Bone
Main Authors: Guo, Wen, Pencina, Karol M, O’Connell, Karyn, Montano, Monty, Peng, Liming, Westmoreland, Susan, Glowacki, Julie, Bhasin, Shalender
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985824/
https://ncbi.nlm.nih.gov/pubmed/28132908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.01.032
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