A carregar...
Seamless phase IIa/IIb adaptive design with the same primary endpoint for proof of concept and dose finding
This paper considers combining a proof of concept (POC) study and a dose finding (DF) study where the POC and the DF share the same primary endpoint. An example based on real study conditions shows that compared to a conventional design the proposed adaptive design tests more active doses, with a sm...
Na minha lista:
| Publicado no: | Contemp Clin Trials Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039539/ https://ncbi.nlm.nih.gov/pubmed/30003170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2018.06.006 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|