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Inactivating hepatic follistatin alleviates hyperglycemia
Unsuppressed hepatic glucose production (HGP) contributes significantly to glucose intolerance and diabetes, which can be modeled by genetic inactivation of hepatic insulin receptor substrate (Irs) 1 and Irs2 (LDKO-mice). We previously showed that glucose intolerance in LDKO-mice is resolved by hepa...
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| Publicado no: | Nat Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039237/ https://ncbi.nlm.nih.gov/pubmed/29867232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0048-0 |
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