Inactivating hepatic follistatin alleviates hyperglycemia

Unsuppressed hepatic glucose production (HGP) contributes significantly to glucose intolerance and diabetes, which can be modeled by genetic inactivation of hepatic insulin receptor substrate (Irs) 1 and Irs2 (LDKO-mice). We previously showed that glucose intolerance in LDKO-mice is resolved by hepa...

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Publicat a:Nat Med
Autors principals: Tao, Rongya, Wang, Caixia, Stöhr, Oliver, Qiu, Wei, Hu, Yue, Miao, Ji, Dong, X. Charlie, Leng, Sining, Stefater, Margaret, Stylopoulos, Nicholas, Lin, Lin, Copps, Kyle D., White, Morris F.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039237/
https://ncbi.nlm.nih.gov/pubmed/29867232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0048-0
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