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Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

Uncoating of the metastable HIV-1 capsid is a tightly regulated disassembly process required for release of the viral cDNA prior to nuclear import. To understand the intrinsic capsid disassembly pathway and how it can be modulated, we have developed a single-particle fluorescence microscopy method t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Márquez, Chantal L, Lau, Derrick, Walsh, James, Shah, Vaibhav, McGuinness, Conall, Wong, Andrew, Aggarwal, Anupriya, Parker, Michael W, Jacques, David A, Turville, Stuart, Böcking, Till
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039174/
https://ncbi.nlm.nih.gov/pubmed/29877795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34772
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