The Role of Capsid Maturation on Adenovirus Priming for Sequential Uncoating

Adenovirus assembly concludes with proteolytic processing of several capsid and core proteins. Immature virions containing precursor proteins lack infectivity because they cannot properly uncoat, becoming trapped in early endosomes. Structural studies have shown that precursors increase the network...

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Dades bibliogràfiques
Autors principals: Pérez-Berná, Ana J., Ortega-Esteban, Alvaro, Menéndez-Conejero, Rosa, Winkler, Dennis C., Menéndez, Margarita, Steven, Alasdair C., Flint, S. Jane, de Pablo, Pedro J., San Martín, Carmen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438990/
https://ncbi.nlm.nih.gov/pubmed/22791715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389957
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