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The Role of Capsid Maturation on Adenovirus Priming for Sequential Uncoating

Adenovirus assembly concludes with proteolytic processing of several capsid and core proteins. Immature virions containing precursor proteins lack infectivity because they cannot properly uncoat, becoming trapped in early endosomes. Structural studies have shown that precursors increase the network...

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Detalhes bibliográficos
Main Authors: Pérez-Berná, Ana J., Ortega-Esteban, Alvaro, Menéndez-Conejero, Rosa, Winkler, Dennis C., Menéndez, Margarita, Steven, Alasdair C., Flint, S. Jane, de Pablo, Pedro J., San Martín, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438990/
https://ncbi.nlm.nih.gov/pubmed/22791715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389957
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