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The Transferrin Receptors, TfR1 and TfR2 Bind Transferrin through Differing Mechanisms

Hereditary hemochromatosis (HH), a disease marked by chronic iron overload from insufficient expression of the hormone hepcidin, is one of the most common genetic diseases. One form of HH (Type III) results from mutations in the transferrin receptor-2 (TfR2). TfR2 is postulated to be a part of signa...

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Publicat a:Biochemistry
Autors principals: Kleven, Mark D., Jue, Shall, Enns, Caroline A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038944/
https://ncbi.nlm.nih.gov/pubmed/29388418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00006
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