Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series

Tumors deficient in DNA mismatch repair are known to display increased susceptibility to immune checkpoint inhibitors due to accumulation of DNA damage and increased neoantigen load. This suggests that deficiency in the BRCA-related DNA repair mechanism may also be a surrogate marker for immunothera...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Gynecol Oncol Rep
Asıl Yazarlar: Matsuo, Koji, Spragg, Samantha E., Ciccone, Marcia A., Blake, Erin A., Ricker, Charité, Pham, Huyen Q., Roman, Lynda D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Case Series
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038829/
https://ncbi.nlm.nih.gov/pubmed/29998185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.06.011
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