Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series

Tumors deficient in DNA mismatch repair are known to display increased susceptibility to immune checkpoint inhibitors due to accumulation of DNA damage and increased neoantigen load. This suggests that deficiency in the BRCA-related DNA repair mechanism may also be a surrogate marker for immunothera...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Gynecol Oncol Rep
Päätekijät: Matsuo, Koji, Spragg, Samantha E., Ciccone, Marcia A., Blake, Erin A., Ricker, Charité, Pham, Huyen Q., Roman, Lynda D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018
Aiheet:
Case Series
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038829/
https://ncbi.nlm.nih.gov/pubmed/29998185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.06.011
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