Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series

Tumors deficient in DNA mismatch repair are known to display increased susceptibility to immune checkpoint inhibitors due to accumulation of DNA damage and increased neoantigen load. This suggests that deficiency in the BRCA-related DNA repair mechanism may also be a surrogate marker for immunothera...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Gynecol Oncol Rep
Main Authors: Matsuo, Koji, Spragg, Samantha E., Ciccone, Marcia A., Blake, Erin A., Ricker, Charité, Pham, Huyen Q., Roman, Lynda D.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Case Series
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038829/
https://ncbi.nlm.nih.gov/pubmed/29998185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.06.011
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker