Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series

Tumors deficient in DNA mismatch repair are known to display increased susceptibility to immune checkpoint inhibitors due to accumulation of DNA damage and increased neoantigen load. This suggests that deficiency in the BRCA-related DNA repair mechanism may also be a surrogate marker for immunothera...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Gynecol Oncol Rep
मुख्य लेखकों: Matsuo, Koji, Spragg, Samantha E., Ciccone, Marcia A., Blake, Erin A., Ricker, Charité, Pham, Huyen Q., Roman, Lynda D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2018
विषय:
Case Series
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038829/
https://ncbi.nlm.nih.gov/pubmed/29998185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2018.06.011
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