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Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE(2) in an in vitro equine inflammation model

Inhibition of prostaglandin E(2) (PGE(2)) production effectively limits inflammation in horses, however nonspecific prostaglandin blockade via cyclooxygenase (COX) inhibition elicits deleterious gastrointestinal side effects in equine patients. Thus, more selective PGE(2) targeting therapeutics are...

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Bibliografiska uppgifter
I publikationen:Vet Immunol Immunopathol
Huvudupphovsmän: Martin, Emily M., Jones, Samuel L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038704/
https://ncbi.nlm.nih.gov/pubmed/29042013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2017.09.008
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