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Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE(2) in an in vitro equine inflammation model
Inhibition of prostaglandin E(2) (PGE(2)) production effectively limits inflammation in horses, however nonspecific prostaglandin blockade via cyclooxygenase (COX) inhibition elicits deleterious gastrointestinal side effects in equine patients. Thus, more selective PGE(2) targeting therapeutics are...
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| Veröffentlicht in: | Vet Immunol Immunopathol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6038704/ https://ncbi.nlm.nih.gov/pubmed/29042013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2017.09.008 |
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