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Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE(2) in an in vitro equine inflammation model
Inhibition of prostaglandin E(2) (PGE(2)) production effectively limits inflammation in horses, however nonspecific prostaglandin blockade via cyclooxygenase (COX) inhibition elicits deleterious gastrointestinal side effects in equine patients. Thus, more selective PGE(2) targeting therapeutics are...
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| Published in: | Vet Immunol Immunopathol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6038704/ https://ncbi.nlm.nih.gov/pubmed/29042013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2017.09.008 |
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