HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

BACKGROUND AIMS: Chronic hepatitis B virus (HBV) infection remains incurable. While HBsAg-specific chimeric antigen receptor (HBsAg-CAR) T-cells have been generated, they have not been tested in animal models with authentic HBV infection. METHODS: We generated a novel CAR targeting HBsAg, and evalua...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cytotherapy
Egile Nagusiak: Kruse, Robert L., Shum, Thomas, Tashiro, Haruko, Barzi, Mercedes, Yi, Zhongzhen, Whitten-Bauer, Christina, Legras, Xavier, Bissig-Choisat, Beatrice, Garaigorta, Urtzi, Gottschalk, Stephen, Bissig, Karl-Dimiter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038120/
https://ncbi.nlm.nih.gov/pubmed/29631939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2018.02.002
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak