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Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism
Local myonecrosis is the main event resulting from snakebite envenomation by the Bothrops genus and, frequently, it is not efficiently neutralized by antivenom administration. Proteases, phospholipases A(2) (PLA(2)) and PLA(2)-like toxins are found in venom related to muscle damage. Functional sites...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037679/ https://ncbi.nlm.nih.gov/pubmed/29985425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28584-7 |
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