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Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver

Oligonucleotide therapeutics have emerged as a third distinct platform for drug discovery within the pharmaceutical industry. Five oligonucleotide-based drugs have been approved by the US FDA and over 100 oligonucleotides drugs are currently at different stages of human trials. Several of these olig...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Miller, Colton M., Tanowitz, Michael, Donner, Aaron J., Prakash, Thazha P., Swayze, Eric E., Harris, Edward N., Seth, Punit P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037193/
https://ncbi.nlm.nih.gov/pubmed/29425080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2017.0709
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