The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

BACKGROUND: Immunotherapy has increasingly become a staple in cancer treatment. However, substantial limitations in the durability of response highlight the need for more rational therapeutic combinations. The aim of this study is to investigate how to make tumor cells more sensitive to T-cell-based...

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Publicado no:J Natl Cancer Inst
Main Authors: McKenzie, Jodi A, Mbofung, Rina M, Malu, Shruti, Zhang, Min, Ashkin, Emily, Devi, Seram, Williams, Leila, Tieu, Trang, Peng, Weiyi, Pradeep, Sunila, Xu, Chunyu, Zorro Manrique, Soraya, Liu, Chengwen, Huang, Lu, Chen, Yuan, Forget, Marie-Andree, Haymaker, Cara, Bernatchez, Chantale, Satani, Nikunj, Muller, Florian, Roszik, Jason, Kalra, Ashish, Heffernan, Timothy, Sood, Anil, Hu, Jianhua, Amaria, Rodabe, Davis, R Eric, Hwu, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037061/
https://ncbi.nlm.nih.gov/pubmed/29267866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx257
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