The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

BACKGROUND: Immunotherapy has increasingly become a staple in cancer treatment. However, substantial limitations in the durability of response highlight the need for more rational therapeutic combinations. The aim of this study is to investigate how to make tumor cells more sensitive to T-cell-based...

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Bibliographic Details
Published in:J Natl Cancer Inst
Main Authors: McKenzie, Jodi A, Mbofung, Rina M, Malu, Shruti, Zhang, Min, Ashkin, Emily, Devi, Seram, Williams, Leila, Tieu, Trang, Peng, Weiyi, Pradeep, Sunila, Xu, Chunyu, Zorro Manrique, Soraya, Liu, Chengwen, Huang, Lu, Chen, Yuan, Forget, Marie-Andree, Haymaker, Cara, Bernatchez, Chantale, Satani, Nikunj, Muller, Florian, Roszik, Jason, Kalra, Ashish, Heffernan, Timothy, Sood, Anil, Hu, Jianhua, Amaria, Rodabe, Davis, R Eric, Hwu, Patrick
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037061/
https://ncbi.nlm.nih.gov/pubmed/29267866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx257
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